COMBINE 2016 - Agenda

Agenda

All meetings will be held at the Crowne Plaza, Newcastle.

Day 1 (Monday, September 19)

Speaker Title Slides Recordings
8:15am Paolo Zuliani & Anil Wipat, Newcastle Welcome Slides
8:30am - 10:00am Session 1
Chair: Chris J. Myers
Modeling
8:30am Sarah Keating, EMBL-EBI SBML in 2016 Slides
9:15am David Nickerson, Auckland CellML, SED-ML, and the Physiome Model Repository Slides
10:00am Break
10:30am - noon Session 2
Chair: Herbert Sauro
Modeling
10:30am Dagmar Iber, ETH Zurich From Networks to Function ­- Computational Models of Organogenesis Slides
11:15am Andrew Millar, Edinburgh What infrastructure to cross the genotype-to-phenotype gap: foundations or flying buttresses?
noon Lunch
1:30pm - 3:00pm Session 3
Chair: Paolo Zuliani
Medical Applications
1:30pm Yujiang Wang, Newcastle Control of epileptic seizures - a computational perspective
2:15pm Alfonso Bueno-Orovio, Oxford Delivering cardiac computational biology to industry and the clinic: Advances towards reshaping future health and care
3:00pm Break
3:30pm - 5:00pm Session 4
Chair: David Nickerson
Models and Data Exchange
3:30pm Carole Goble, Manchester FAIRDOM - FAIR asset management and sharing experiences in Systems and Synthetic Biology Slides
4:15pm Chris J. Myers, Utah A Standard Enabled Workflow for Synthetic Biology Slides
5:00pm Wrapup
5:30pm Social Event
7:00pm Banquet (Crowne Plaza)


Day 2 (Tuesday, September 20)

Speaker Title Slides Recordings
8:30am - 10:00am Session 5
Chair: Goksel Misirli
Software
8:30am David Nickerson, Auckland OpenCMISS-Osmium: helping PMR support the VPH requirements for identifiable and discoverable computational models Slides
8:45am Herbert Sauro, Washington pathwayDesigner: A SBML compliant network simulation and design tool Slides
9:00am Matthias König, Humboldt cy3sbml: a Cytoscape app for SBML Slides
9:15am Curtis Madsen & Nicholas Roehner, Boston Nona Research Foundation - Creating a SynBio Software Commons Slides
9:30am Discussion
10:00am Break/Posters
10:30am - noon Session 6
Chair: Curtis Madsen
Synthetic Biology
10:30am Goksel Misirli, Newcastle Data Integration and Mining for Synthetic Biology Design Slides
10:45am Hiroyuki Kuwahara, KAUST A new thermodynamics-based approach to aid the design of natural-product biosynthetic pathways Slides
11:00am Nicholas Roehner, Boston How to Remember and Revisit Many Genetic Design Variants Automatically Slides
11:15am Bryan Bartley, Washington Version and Variant Control for Synthetic Biology Slides
11:30am Discussion
noon Lunch
1:30pm - 3:00pm Session 7 Breakouts
Leader: Anil Wipat, Track: SBOL SBOL: Host Context (remote attendance via BlueJeans)
Leader: David Nickerson SED-ML: L1V3 Status/Review (remote attendance via BlueJeans)
3:00pm Break/Posters
3:30pm - 5:00pm Session 8 Breakouts
Leader: Lucian Smith, Track: SBML SBML L3v2 (and libsbml/test suite support) (remote attendance via BlueJeans)
Leader: Herbert Sauro, Track: SBOL SBOL: Website, FAQ, and Tutorials (remote attendance via BlueJeans)
5:00pm Wrapup


Day 3 (Wednesday, September 21)

Speaker Title Slides Recordings
8:30am - 10:00am Session 9
Chair: Anil Wipat
Invited Talks
8:30am Martin Golebiewski, HITS COMBINE and ISO/TC 276 Biotechnology: From grassroots community standards to official ISO standards Slides
9:15am Daryl Shanley, Newcastle Modelling ageing to enhance a healthy lifespan Slides
10:00am Break/Posters
10:30am - noon Session 10
Chair: Frank Bergmann
Web
10:30am Vincent Noel, Instituto Butantan SigNetSim : A web-based framework for designing kinetic models of molecular signaling networks Slides
10:45am Andreas Draeger, Tuebingen The ZBIT Systems Biology Software and Web Service Collection Slides
11:00am Martin Peters, Rostock SED-ML support in JWS Online Slides
11:15am Martin Golebiewski, HITS The NormSys registry for modeling standards in systems and synthetic biology Slides
11:30am Discussion
noon Lunch
1:30pm - 3:00pm Session 11 Breakouts
Leader: Sarah Keating, Track: SBML SBML Math packages (remote attendance via BlueJeans)
Leader: Robert Sydney Cox, Track: SBOL SBOL Visual / SBGN (remote attendance via BlueJeans)
3:00pm Break/Posters
3:30pm - 5:00pm Session 12 Breakouts
Leader: James McLaughlin, Track: SBOL SBOL: Ontologies and URI Best Practices (remote attendance via BlueJeans)
Leader: Kieran Alden Standards for storing and exchanging agent-based models (remote attendance via BlueJeans)
5:00pm Wrapup


Day 4 (Thursday, September 22)

Speaker Title Slides Recordings
8:30am - 10:00am Session 13
Chair: Martin Golebiewski
Ermerging Standards
8:30am Fengkai Zhang, NIH SBML Multi - From Specification to Application Slides
8:45am Samuel Friedman, USC MultiCellDS: a community-developed standard for curating microenvironment-dependent multicellular phenotype data as digital cell lines, snapshots, and collections
9:00am David Nickerson, Auckland Exploiting Electronic Health Record Standard openEHR to Manage Experimental Data in Computational Physiology Slides
9:15am Kieran Alden, York Approaches for Developing Computational Models of Immune System Formation and Function Slides
9:30am Discussion
10:00am Break/Posters
10:30am - noon Session 14
Chair: Andreas Draeger
Simulation
10:30am Kiri Choi, Washington Tellurium: A Python Based Modeling and Reproducibility Platform for Systems Biology Slides
10:45am Leandro Watanabe, Utah Modeling and Simulating Hybrid SBML Models Slides
11:00am Fabian Fröhlich, Helmholtz Zentrum München AMICI: An ODE simulation framework for sensitivity analysis of large-scale models Slides
11:15am J Kyle Medley, Washington High-performance Model Simulation with libRoadRunner
11:30am Discussion
noon Lunch
1:30pm - 3:00pm Session 15 Breakouts
Leader: Bryan Bartley, Track: SBOL SBOL Sequence Layer (remote attendance via BlueJeans)
Leader: Dagmar Waltemath, Track: SED-ML/SBML SED-ML/SBML & qual (remote attendance via BlueJeans)
3:00pm Break/Posters
3:30pm - 5:00pm Session 16 Breakouts
Leader: Tramy Nguyen, Track: SBOL SBOL Interaction Definitions (remote attendance via BlueJeans)
Leader: Fengkai Zhang, Track: SBML SBML Multi Package (remote attendance via BlueJeans)
5:00pm Wrapup


Day 5 (Friday, September 23)

Speaker Title Slides Recordings
8:30am - 10:00am Session 17
Chair: Dagmar Waltemath
Model Exchange
8:30am Maciej J Swat, EMBL-EBI PharmML - exchange format for models used in quantitative system pharmacology and pharmacometrics Slides
8:45am Augustin Luna, BioPAX Consortium Biological Pathway Exchange (BioPAX) Format and Pathway Commons Update Slides
9:00am Miguel de Alba, Federal Institute for Risk Assessment (BfR) Introducing FSK-ML - an SBML derivate for description and exchange of executable script based models Slides
9:15am Tramy Nguyen, Utah Interconversion Between BioPAX and SBML Slides
9:30am Discussion
10:00am Break/Posters
10:30am - noon Session 18
Chair: Nicholas Roehner
Visual Standards
10:30am Alexander Mazein, European Institute for Systems Biology and Medicine Comprehensive representation of disease mechanisms on multiple layers of granularity in SBGN PD and AF Slides
10:45am Robert Sidney Cox, Caltech The Visual Protein Design Language Slides
11:00am Jacob Beal, BBN Progress Report on Development of SBOL Visual 2.0 Slides
11:15am Vasundra Toure, Rostock Visualising differences in SBML models using SBGN and BiVeS Slides
11:30am Discussion
noon Lunch
1:30pm - 3:00pm Session 19 Breakouts
Leader: Anil Wipat, Track: SBOL General Discussion/Hacking (remote attendance via BlueJeans)
Leader: David Nickerson, Track: SED-ML SED-ML: New Output Types, Plots, Roadmap (remote attendance via BlueJeans)
3:00pm Break/Posters
3:30pm - 5:00pm Session 20 Breakouts
Leader: Dagmar Waltemath COMBINEd Annotations (remote attendance via BlueJeans)
5:00pm Wrapup


Day 6 (Saturday, September 24)

The SBGN Workshop/Hackathon will be held in the same venue (Crowne Plaza).


Posters

Presenter Title Poster
Nima Afshar, Auckland Computational Modelling of Glucose uptake in enterocytes using CellML


Kieran Alden, York Approaches for Understanding the Relationship Between a Computational Model and Captured Real-World Phenomena


Florian Auer, Goettingen Bringing Pathway Knowledge to Systems Medicine Approaches


Petronela Buiga, Manchester Application of systems biology regulation of HER2 signalling in breast cancer therapy


Kiri Choi, University of Washington Using SBML to Model Cellular Automata


Harold Fellerman, Newcastle A temperature-dependent computational model of the PCR reaction


Matthias König, Humboldt University Personalized liver function tests: A Multiscale Computational Model Predicts Individual Human Liver Function From Single-Cell Metabolism


Goksel Misirli, Newcastle Data Integration and Mining for Synthetic Biology Design


Goksel Misirli, Newcastle Modular Composition of Synthetic Biology Designs using Rule-Based Models


Jeremy Revell, Newcastle Cross Entropy Method For Stochastic Parameter Inference


James Scott-Brown, Oxford Visual Comparison of SBML Models


Vasundra Toure, Rostock A demonstration of a fully-featured COMBINE Archive


Vasundra Toure, Rostock Designing informative SBGN maps using SBGN-ED


Brijesh S. Yadav, Tel Aviv Multidimensional patterns of metabolic response in abiotic stress-induced growth of Arabidopsis thaliana